Tag: tumor microenvironment

New research shows that FAP-positive pericyte-like cells in glioblastoma promote the differentiation of monocytes into immunosuppressive tumor-associated macrophages.

The prospective SARC-LUNG study links circulating immunometabolic biomarkers such as sRAGE and FGF21 with survival and immune microenvironment profiles in ...

Researchers have identified an energy-stress-induced long non-coding RNA called GIRGL that drives glucose metabolism reprogramming in lung adenocarcinoma by interacting ...

A new mouse study finds that combining the PARP inhibitor olaparib with radiotherapy improves tumor control in oral squamous cell ...

A new review synthesizes decades of evidence showing that selective COX-2 inhibitors can suppress tumor initiation, growth and immunotherapy resistance ...

Colorectal cancer has long been divided into two camps at the genetic level: tumors carrying mutations in the KRAS gene ...

A single intratumoral injection of the experimental TLR4 agonist EmT4™ transformed an immunologically quiet canine soft tissue sarcoma into an ...

A new review explains how radiation-induced CCL2/CCR2 signaling recruits immunosuppressive myeloid cells and remodels the tumor microenvironment, and why combining ...

A new computational platform reveals how collagen architecture and myeloid cells cooperate to trap therapeutic T cells in pancreatic tumors, ...

In a discovery that may finally explain one of the most confounding paradoxes in cancer biology, researchers at the Salk ...