Galectin-9 Emerges as a Key Driver of Immune Evasion in Cervical Cancer Progression
A multi-omics study traces cervical carcinogenesis from normal tissue to invasive cancer and identifies galectin-9-driven immune evasion as a promising ...
Tag: tumor microenvironment
Scientists Turn Single-Cell Data Into Personalized Immune Cell Designs for Breast Cancer
A new computational pipeline translates single-cell immune fingerprints from triple-negative breast cancer patients into ranked engineering recommendations for synthetic immune ...
New Web Tool Lets Researchers Hand-Pick Cells Directly on Spatial Omics Images
Austrian researchers have developed Spatialgater, a free R Shiny web tool that lets scientists draw polygon gates to select individual ...
Transfer Learning Reconstructs the Signaling Histories of Single Cells
A new computational framework called IRIS uses perturbation screening data and transfer learning to reconstruct the signaling states and histories ...
T Cells Can Wipe Out Tumors Without Ever Recognizing Them
New research shows that activating bystander T cells inside tumors triggers antigen-independent tumor killing through cytokines, nitric oxide and innate ...
Flavonoid Diosmetin Targets Endothelial Enzyme to Rewire Lung Cancer Immune Defenses
New research identifies endothelial CYP3A5 as a functional vulnerability in lung adenocarcinoma and shows that the natural flavonoid diosmetin suppresses ...
Neutrophils in Cancer: The Immune Cells That Turn Traitors and Healers
A comprehensive new review reveals how neutrophils, the immune system's most abundant white blood cells, are co-opted by tumors to ...
Bile Acids Emerge as Master Regulators Linking Gut Microbes, Immunity and Cancer
A new commentary in Holistic Integrative Oncology argues that bile acids act as master signaling molecules linking liver metabolism, gut ...
Tumor Vesicles Loaded with SPP1 Rewire Fibroblasts to Shield Lung Cancer from Immunity
New research shows that lung adenocarcinoma cells package the protein SPP1 into extracellular vesicles to reprogram fibroblasts into an MMP11-positive ...
Radium-223 Therapy Lowers PD-L1 in Prostate Cancer Bone Metastases, PET Study Shows
A prospective imaging study shows that radium-223 significantly reduces PD-L1 expression and depletes immune cells in prostate cancer bone metastases, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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