Engineered Bacteria Deliver Two-in-One Immunotherapy Directly to the Pleural Cavity in Mice
An engineered non-pathogenic bacterium carrying a PD-L1 blocker and IL-15 significantly suppressed pleural tumors and fluid buildup in a mouse ...
Tag: tumor microenvironment reprogramming
DNA repair kinase PRKDC helps liver cancer hide from macrophage attack
A new study reveals that PRKDC, a gene known for DNA repair, drives immune evasion in hepatocellular carcinoma by pushing ...
Immune Cell Signal Reveals How Triple Therapy Reshapes Liver Tumors
New research shows that triple therapy for unresectable liver cancer is associated with denser, more mature intratumoral tertiary lymphoid structures ...
Noninvasive Physical Stimulation Reprograms Tumor Macrophages for Cancer Immunotherapy
Cancer researchers are turning to an unexpected set of tools—sound waves, beams of light, electrical pulses, magnetic nanoparticles and carefully ...
Mouth Stem Cells Show Promise in Overcoming Brain Cancer Defenses
Researchers at the University of Reading have uncovered a compelling new approach to combat glioblastoma, the most aggressive and lethal ...
Immune-Remodeling mRNAs Drive Lasting Cancer Immunity
In a groundbreaking advance that promises to redefine the landscape of cancer immunotherapy, researchers have engineered a novel delivery system ...
Nanoscale Ferrocene-Modified Covalent Organic Frameworks Enable Ferroptosis-Driven Sonodynamic Therapy to Combat Breast Cancer and Bone Metastasis
Breast cancer continues to pose a formidable challenge in the field of oncology, especially with its propensity for metastasizing to ...
Pioneering First-in-Human Trial Demonstrates Safety and Efficacy of Novel Immune Cell Therapy in Advanced Lymphoma
A groundbreaking advancement in the treatment of difficult-to-treat lymphomas has emerged from the research laboratories at The University of Texas ...
11-Amino-Acid Peptides Block Colorectal Cancer Immune Evasion
In a groundbreaking study published in Cell Research, researchers have unveiled a novel approach to thwart immune evasion mechanisms employed ...
SH3BP5: A Key to DLBCL Immunotherapy Progress
In a groundbreaking study published in the Journal of Translational Medicine, a team of researchers has illuminated a critical pathway ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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