Erianin curbs prostate cancer growth in mice and dampens STAT3 signaling
Preclinical experiments found that erianin reduced prostate cancer cell activity and mouse tumor growth while lowering phosphorylation of the STAT3 ...
Tag: tumor growth
Mebendazole restores gefitinib activity by inducing DNA damage in resistant lung cancer cells
Mebendazole combined with gefitinib increased DNA damage and suppressed growth in preclinical models of gefitinib-resistant non-small cell lung cancer.
Mouse study identifies PLD1 target in non-small cell lung cancer
A mouse study found that directly reducing lung cancer cells’ dependence on phospholipase D1 significantly slowed tumor growth, but clinical ...
NDUFS1 links mitochondrial respiration to aggressive breast cancer behavior
A preclinical study links elevated NDUFS1, a mitochondrial complex I subunit, to breast cancer progression through increased respiration and PROX1–c-Myc ...
Smart bomb combination curbs metastatic triple-negative breast cancer in models
A CD276-targeted antibody-drug conjugate combined with mitochondrial-disrupting gene therapy outperformed either treatment alone in two preclinical models of metastatic triple-negative ...
Cancer Cells Selectively Strip Gene-Rich Regions of the Y Chromosome to Fuel Tumor Growth
A new study shows that cancer cells selectively erode gene-rich regions of the Y chromosome, disrupting regulatory pathways and opening ...
Mitochondrial DNA Copy Number Emerges as a Key Player in Cancer Progression
New research in The FEBS Journal links mitochondrial DNA copy number in cancer cells to mutational load, tumor growth gene ...
Small Thyroid Cancers Grow When Surgery Is Delayed, Study Warns
A retrospective study of 75 patients found that most medullary thyroid microcarcinomas grew during delayed surgery, with larger tumors linked ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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