New computational tool maps the cell-state crosstalk that decides survival in IDH-mutant glioma
A new computational framework called CSI-TME infers prognostic interactions between cell states in the tumor microenvironment from bulk RNA-seq data, ...
Tag: tumor evolution
After Nine Years of ALK Drugs, Lung Cancer Switches Gears—and a Second Mutation Saves the Day
A case report documents an ALK-rearranged lung cancer patient who acquired a druggable EGFR L858R mutation after nearly nine years ...
Circular DNA Emerges as an Epigenetic Engine Driving Cancer’s Rapid Adaptation
A new review in Molecular Cancer argues that extrachromosomal DNA acts as a dynamic epigenetic reprogramming platform that reshapes chromatin, ...
Cancer’s Family Tree Gets a Map: Lineage Tracing Reveals How Tumors Grow and Spread
A new Nature Genetics study combines spatial transcriptomics and lineage tracing to map how lung tumor subclones expand, reshape their ...
Pancreatic Cancer’s Moving Target: New Framework Calls for Continuously Evolving Treatment
A new review proposes a Dynamic Precision Oncology framework that monitors pancreatic cancer's evolving resistance mechanisms through longitudinal genomic, liquid ...
Mutational Fingerprints Reveal the Hidden Forces Driving Prostate Cancer
A new Nature study integrates multiple classes of genomic mutations to define the distinct mutational processes that shape prostate cancer ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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