TAKO ranks gene knockout effects from wild-type single-cell data in seconds, no training required
Researchers introduced TAKO, a fast and interpretable method that ranks likely targets of a single-gene knockout using only wild-type single-cell ...
Tag: TREM2
Brain organoids without immune cells may miss the real story of neurodegeneration
A PLOS Biology Perspective argues that immune and vascular cells, especially microglia, must be core components of neural organoids used ...
Single-cell atlas of human liver pinpoints scar macrophages as drug target for fibrosis
A 649,295-cell single-cell atlas of human livers has revealed a pro-inflammatory OLR1-positive scar-associated macrophage population that expands across chronic liver ...
Immune Checkpoint TREM2 Emerges as a Switch to Supercharge CAR Macrophages Against Breast Cancer
New research shows that blocking the TREM2 receptor reprograms HER2-targeted CAR macrophages from suppressive to inflammatory, tumor-engulfing cells in breast ...
Smart Nanoparticles Reprogram Tumour Defenses to Boost Immune Attack on Cancer
Adelaide University researchers have developed mRNA lipid nanoparticles that reprogram immunosuppressive tumour-associated macrophages to recruit cancer-fighting T cells, showing reduced ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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