Hidden RNA Errors Found at the Synapse in Frontotemporal Dementia
Multi-omic profiling of synaptosomes from C9ORF72-frontotemporal dementia brain and patient-derived neurons reveals widespread synaptic molecular disruption and, for the first ...
Tag: Transcriptomics
Gene Networks Point to Interferon Decline as Driver of Severe Dengue in India
A whole-blood transcriptomic study of 112 dengue patients in New Delhi links depressed interferon responses and altered glycosylation pathways to ...
New High-Throughput Screening Platform Accelerates the Hunt for Molecular Glue Degraders
Researchers have built a scalable transcriptomic screening platform that uses gene expression signatures and CRBN knockout cell models to systematically ...
Sacred Lotus Gene Offers New Shield Against Cadmium’s Toxic Grip
Scientists identified a lotus E3 ubiquitin ligase, NnRNF217, that boosts cadmium tolerance in plants by supercharging antioxidant enzyme activity and ...
Buffalo Milk RNA Reveals the Metabolic Signature of High-Yield Dairy Animals
An integrated analysis of RNA extracted from buffalo milk reveals that high-yielding animals show enhanced metabolic and biosynthetic gene activity ...
Jumping Genes Divide the Animal Kingdom into Sea and Land Clades
A transcriptome-wide survey of 315 animal species confirms that Copia retrotransposon clades are strongly partitioned between marine and terrestrial environments ...
Prenatal BPA Exposure Rewires the Cerebellum Differently in Male and Female Rat Offspring
A new rat study finds that prenatal exposure to bisphenol A disrupts cerebellar gene expression and motor behavior in sex-specific ...
Immune Cells Cluster, Not Crowd, in Melanoma That Spreads to the Brain
A Dutch study finds that melanoma brain metastases harbor far fewer but more tightly clustered immune cells than other metastases, ...
In a Dish, Male and Female Macrophages Wage Inflammation Differently
Researchers coaxed stem cells from male and female donors into macrophages and found that inflammation dramatically widens the genetic and ...
Whole-Transcriptome Sequencing Maps Host RNA Changes During Chicken Anemia Virus Infection
A whole-transcriptome sequencing study of CIAV-infected MDCC-MSB1 cells identifies thousands of altered RNAs and highlights PTEN and ARHGEF12 as candidate ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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