Snail2 Emerges as the Master Switch Behind Partial EMT, Metastasis and Development
A comprehensive review in Cell Death Discovery maps how the transcription factor Snail2 governs partial epithelial-mesenchymal transition, driving both embryonic ...
Tag: transcription factor
Two Cancer Genes Pull in Opposite Directions in Papillary Thyroid Tumors
A study of 125 papillary thyroid cancer patients finds that EGFR and GLI1 are both upregulated in tumors but inversely ...
Oocyte Gene Figla May Steer Ovarian Reserve Formation Through Ywhab, Mouse Study Suggests
A new mouse and cell study identifies Ywhab as a candidate downstream target of the oocyte transcription factor Figla during ...
Tea’s Astringent Secret: Scientists Uncover the Genetic Switch Behind Quercetin
Researchers have identified a WRKY transcription factor, CsWRKY22, that activates the flavonol synthase gene CsFLSd and thereby controls quercetin accumulation ...
CRISPR Knockout of a Single Gene Supercharges Soybean’s Health-Boosting Isoflavones
Researchers used CRISPR/Cas9 to knock out the GmMYB100 repressor gene in soybean, boosting seed daidzein levels nearly threefold and genistein ...
A Tiny Glycine Repeat May Have Helped Mammals Grow Hair, Study Suggests
Researchers report that a polyglycine repeat inserted into the Hoxc13 transcription factor during mammalian evolution dramatically expanded its genome-wide DNA ...
Heat Waves Turn Whiteflies Into Better Virus Vessels via a Single Stress Switch
A new study shows that heat shock factor in the whitefly Bemisia tabaci binds directly to the tomato yellow leaf ...
Gallic Acid Blocks Prostate Cancer Progression by Disrupting a Key Molecular Switch
A Chinese Medical Journal study shows that the natural compound gallic acid suppresses prostate cancer progression by binding the NF-κB ...
Green Gene Switch Found That Paints Young Peaches and Boosts Fruit Photosynthesis
Researchers have identified the peach gene PpAPRR2 as a nuclear transcription factor that promotes chlorophyll accumulation and chloroplast development in ...
Hidden Molecular Switch Links H. pylori Infection to Aggressive Gastric Cancer
A new study reveals how the ONECUT2-YOD1-STAT3-PD-L1 signaling axis drives malignant progression and immune evasion in H. pylori-associated gastric cancer.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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