Vaccine adjuvant AS01 induces trained immunity and slows tumor growth in mice
A new study in Myeloid Cells reports that the vaccine adjuvant AS01 induces trained immunity in human monocytes and slows ...
Tag: trained immunity
How Microbial Sensing May Drive Persistent Pain After Infection Clears
A new mini-review proposes that persistent microbial sensing through pattern recognition receptors may bridge acute infection and long-lasting pain.
Acute versus chronic liver disease drives different cardiac injury programmes, review proposes
A new review proposes an 'acute storm versus chronic siege' framework distinguishing how acute and chronic liver disease injure the ...
BCG vaccine reduces tau pathology and improves memory in dementia-model mice
A controlled study of mice with tau pathology found that BCG vaccination reduced brain inflammation and tau deposition and improved ...
Mouse Studies Map the Broad Immunomodulatory Reach of Bacterial Lysates
A systematic review of 34 murine studies published from 2010 to 2025 finds bacterial lysates show consistent preclinical immunomodulatory effects ...
Systematic review finds limited direct evidence of macrophage environmental memory
A systematic review of 119 studies found that only four directly demonstrated persistence or altered recall in macrophages or monocytes ...
Nanoparticles That Help Cells Remember: A New Bid to Make mRNA Therapies Last Longer
A new hypothesis proposes that programmable lipid nanoparticles may shape cellular memory systems to extend the durability of mRNA vaccines ...
How the Immune System Matures, Ages, and Defies Time
A new review maps how human immunity develops from a deliberately tolerogenic newborn state through adult peak performance to the ...
How Metabolic Syndrome May Prime the Brain’s Immune Cells and Weaken Its Brakes Against Seizures
A new hypothesis-driven framework proposes that metabolic syndrome may prime the brain's immune cells through trained-immunity-like mechanisms and weaken parvalbumin ...
Innate Immune Memory: How Epigenetic and Metabolic Rewiring Shapes Health and Disease
A new review in the Journal of Molecular Medicine explains how trained immunity, driven by epigenetic and metabolic reprogramming of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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