In human amniotic epithelial cells, Ureaplasma urealyticum impairs IFN-γ–inducible IDO1 defense via TLR2-dependent SOCS1 induction, amplifying inflammatory chemokine production.
A pre-specified neutrophil-degranulation programme was elevated in acute respiratory distress syndrome pairs and exhibited ex vivo sensitivity to GM-CSF and ...
A new study in Cell Death Discovery shows that MCP-1 promotes a T-cell-supportive phenotype in specific mesenchymal stem cell populations ...
A mouse study demonstrates that neutrophil extracellular traps exacerbate renal ischemia-reperfusion injury by activating Th17-driven inflammation through TLR2 and STAT3 ...
Researchers identified the TLR2/TLR4-binding sequences of the matrix protein biglycan and showed that synthetic peptides carrying these motifs reduce inflammation ...
Researchers report that the microRNA miR-21a-5p protects the injured blood–brain barrier in cellular models by directly targeting DDX58, suppressing TLR2/NF-κB ...
Researchers report that Y RNAs on the surface of human monocytes bind extracellular histones and amplify TLR2/TLR4-driven inflammatory signaling, with ...
A single 2 Gy prophylactic dose of liver radiation reprograms hepatic immune cells via an SAA1–TLR2–CXCL10 signaling axis to recruit ...
A recombinant adhesion protein from the gum disease bacterium Porphyromonas gingivalis activates dendritic cells through TLR2 and boosts the anti-tumor ...
A new disubstituted thymoquinone derivative designated TQ13 inhibited TLR2 and TLR4 signaling and protected kidney function in diabetic rats, offering ...
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