Surface Y RNAs Turn Monocytes into Inflammatory Amplifiers
Researchers report that Y RNAs on the surface of human monocytes bind extracellular histones and amplify TLR2/TLR4-driven inflammatory signaling, with ...
Tag: TLR2
A Tiny Dose of Radiation Could Stop Cancer From Spreading to the Liver
A single 2 Gy prophylactic dose of liver radiation reprograms hepatic immune cells via an SAA1–TLR2–CXCL10 signaling axis to recruit ...
Gum Disease Protein Mfa1 Supercharges Anti–PD-L1 Cancer Immunotherapy in Mice
A recombinant adhesion protein from the gum disease bacterium Porphyromonas gingivalis activates dendritic cells through TLR2 and boosts the anti-tumor ...
Black Cumin Compound Derivative Shows Promise Against Diabetic Kidney Disease
A new disubstituted thymoquinone derivative designated TQ13 inhibited TLR2 and TLR4 signaling and protected kidney function in diabetic rats, offering ...
Immune Cells That Kill Superbug Bacteria Directly Offer New Hope for Hard-to-Treat Lung Infections
New research in mice shows that IL-17A-producing γδ T cells directly kill Mycobacterium abscessus in the lung, revealing a promising ...
Evolutionary history may explain why COVID-19 affects some people more severely
Viruses do not encounter a blank biological landscape when they infect humans. They meet an immune system shaped by thousands ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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