Tiny RNA switches revealed in the bone marrow behind allergic eosinophilia
A new study maps how IL-33-driven microRNA programs in the lungs and bone marrow coordinate eosinophil production and airway recruitment ...
Tag: tissue-specific gene regulation
One Obesity Gene Variant Rewires Nearly 100 Genes in Fat Cells, Study Finds
Researchers combined single nucleus RNA-sequencing with GWAS and UK Biobank data to show that an obesity-linked variant in SREBF1 allele-specifically ...
Scientists design tissue-specific mammalian enhancers that function in mouse embryos
A new study reports a step toward treating mammalian gene regulation as an engineering problem: rather than searching through the ...
Targeted viral vectors silence vitamin D receptors in mouse bones and muscles
A new study has demonstrated a way to reduce vitamin D receptor activity selectively in bone or muscle in living ...
Expanded Registry of Candidate Cis-Regulatory Elements
In a groundbreaking study published recently in Nature, researchers have delved deep into the enigmatic world of gene regulation, revealing ...
Unlocking Noncoding Variants’ Influence on Gene Expression
In the rapidly evolving field of genomic science, the ability to predict how noncoding mutations influence gene expression has increasingly ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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