H&E Slide Spatial Features Explain Gene Expression Beyond Cell-Type Mix
Spatial features extracted from routine H&E slides of 471 normal prostate tissue samples significantly improved gene expression models for 2,330 ...
Tag: Tissue microenvironment
New ESMF Method Sharpens Cell-Type Estimates from Bulk RNA Sequencing Data
A new deconvolution framework called ESMF uses single-cell reference data, negative binomial noise modeling and dual-validated marker selection to estimate ...
Tissue Around Breast Microcalcifications Outshines the Calcium Itself in Micro-CT Study
A study of 3504 individual breast microcalcifications scanned with high-resolution 3D micro-CT shows that the tissue surrounding each calcium deposit ...
Pregnancy and Breastfeeding Leave Lasting Marks on Breast Tissue Stroma
A new study links reproductive history, including parity, age at first pregnancy, and breastfeeding, to distinct stromal marker expression patterns ...
Hidden messengers: matrix-bound vesicles rewrite the rules of tissue signalling
A new review argues that matrix-bound extracellular vesicles retained within the extracellular matrix form a distinct, tissue-specific signalling population with ...
T Cells Mobilize to Combat Gut Infections
In the complex environment of the human gut, immune cells play a crucial role in balancing the delicate dance of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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