Prostate cancer stem-cell targeting reviewed for therapy resistance
A narrative review identifies prostate cancer stem-like cells as plausible contributors to treatment persistence and relapse while concluding that most ...
Tag: therapy resistance
Hidden Cell-to-Cell Messaging Networks Drive Triple-Negative Breast Cancer Resistance
A new review argues that triple-negative breast cancer's heterogeneity and therapy resistance emerge from spatially organized paracrine signaling networks between ...
Two Molecular Machines, One Cancer Engine: How Deubiquitinases and m6A RNA Tags Talk to Each Other
A new review in Molecular Cancer maps the bidirectional crosstalk between deubiquitinases and m6A RNA modification, revealing a coupled regulatory ...
The Hidden Switch That Helps Breast Cancer Survive and Resist Treatment
A comprehensive new review maps how NF-κB signalling drives breast cancer progression, subtype-specific therapy resistance and tumour-microenvironment crosstalk, and argues ...
A Single tRNA Molecule Controls Whether Prostate Cancer Stays Vulnerable to Therapy
A new Nature study shows that the dosage of a single transfer RNA, tRNA1Arg(UCU), acts as a reversible molecular switch ...
Treatment pulses reshape nutrient landscapes and decide whether resistant mutants escape
A yeast-based therapy-mimicry assay paired with a digital twin reveals that intermittent treatment pulses control resistance escape by reshaping spatial ...
How Shapeshifting Tumor Cells Outsmart Cancer Treatment
A new review explains how tumor cells reversibly switch identities through epigenetic and microenvironmental programs, driving metastasis and therapy resistance.
Iron-Powered Cell Death Emerges as Double-Edged Sword in Cancer’s Microenvironment
A new review in Medical Oncology maps how the tumor microenvironment can either amplify or suppress ferroptosis, the iron-dependent cell ...
How Lung Cancer Rewires Fat Metabolism to Grow, Spread, and Evade Treatment
A new review in the Journal of Translational Medicine maps how non-small cell lung cancer rewires lipid metabolism to fuel ...
Chemical Tags on RNA Drive Cancer Spread and Treatment Failure, Review Finds
A comprehensive review in Molecular Cancer details how chemical modifications to RNA molecules regulate tumor metastasis and therapy resistance, opening ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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