Novel NPEPL1 Inhibitor C301-9181 Shows Promise Against Liver Cancer
Hepatocellular carcinoma, the most common form of primary liver cancer, remains one of the deadliest malignancies worldwide, with prognosis poor ...
Tag: therapeutic
Single-Cell Atlas Reveals How Sonic Hedgehog Medulloblastoma Comes Back
Medulloblastoma is the most common malignant brain tumor in children, and the sonic hedgehog (SHH) subtype accounts for roughly one-third ...
Oral microbiota–immune crosstalk in the pathogenesis and progression of periodontitis: mechanisms and therapeutic potential
A sweeping new review maps the two-way molecular conversation between the oral microbiome and the immune system in periodontitis, revealing ...
Gardenia-Derived Genipin Emerges as a Therapeutic Candidate for Peripheral Nerve Diseases
A new perspective proposes that the gardenia-derived compound genipin exerts its therapeutic effects in peripheral nerve diseases primarily through crosslinking ...
Scientists Map the Matrix War Inside Arthritic Knees
Knee osteoarthritis has long been dismissed as simple wear and tear, the inevitable price of a life spent walking, running, ...
How Doxorubicin Hijacks the Heart’s Cellular Cleanup Crew — and Why It Matters
A sweeping review reveals how the chemotherapy drug doxorubicin breaks the heart's mitochondrial and ER recycling systems at multiple checkpoints, ...
IL-24 steps out of the shadows as a central regulator of liver disease
A new review in Molecular Biology Reports maps how interleukin-24, once known only as a melanoma differentiation gene, regulates hepatocellular ...
Shining Light on the Brain: How Photobiomodulation Could Tame Neuroinflammation
A new review in Frontiers in Neurology examines how low-intensity red to near-infrared light may modulate the neuroinflammatory processes shared ...
Novel perspective on immune cell regulation in gastrointestinal inflammation: the role of extracellular vesicles and therapeutic prospects
Extracellular vesicles have moved from being regarded as cellular debris to being recognized as active participants in intercellular communication, and ...
Asparaginase Levels Fall Short in Indian Children With High-Risk Leukemia, Pilot Study Finds
A pilot study from New Delhi finds consistently subtherapeutic trough asparaginase levels in Indian children with high-risk acute lymphoblastic leukemia, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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