Polyamine Metabolism Emerges as a Central Player in Neurological Disease
A new review links dysregulated polyamine metabolism to Alzheimer's, Parkinson's, ALS, and other neurological disorders, outlining molecular mechanisms and emerging ...
Tag: therapeutic targets
Hidden Mitochondrial Transporters May Expose New Vulnerabilities in Colorectal Cancer
A new review highlights how three mitochondrial metabolite transporters are deregulated in colorectal cancer and jointly shape tumor metabolism, epigenetic ...
Argininosuccinate Signal Fuels Carbon Replenishment in Leukaemia Cells
New research in Nature Metabolism shows that phosphorylated ASS1 in B cell acute lymphoblastic leukaemia produces argininosuccinate, which activates NT5C2 ...
Amyloid-β Impairs Glymphatic Flow via Astrocyte Cholesterol
In a groundbreaking study that promises to reshape our understanding of Alzheimer’s disease (AD) at the molecular and cellular levels, ...
PCBP1-AS1 Drives Pancreatic Cancer Liver Metastasis
In a groundbreaking study poised to reshape our understanding of pancreatic cancer metastasis, researchers have unveiled the pivotal role of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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