Tag: tertiary lymphoid structures

Researchers have discovered a clonally coordinated network of suppressive regulatory T cells that spans the blood, lymph nodes and airways ...

By combining spatial and single-cell transcriptomics, researchers have mapped previously unknown immunosuppressive niches in colorectal cancer, including SPP1-positive macrophage rings ...

A new spatial transcriptomics study shows that tertiary lymphoid structures in tumors are spatially zoned immune organs whose core-periphery organization ...

A new grading system for tertiary lymphoid structures in glioblastoma tissue identifies patients with significantly longer survival and may guide ...

New spatial profiling research shows that the positioning of cytotoxic T cells around tumor blood vessels predicts which non-small cell ...

A new study links CEACAM1 expression and dysregulated SHP-1, LCK, and ZAP70 signaling to the functional exhaustion of follicular cytotoxic ...

New research shows that triple therapy for unresectable liver cancer is associated with denser, more mature intratumoral tertiary lymphoid structures ...

A new review in the Journal of Molecular Medicine maps how heterogeneous follicular helper T cell subsets are regulated by ...

An integrated single-cell and spatial transcriptomic study has identified a triple-negative breast cancer-enriched malignant epithelial program, EP5, linked to aggressive ...

A stage-spanning single-cell atlas of bladder cancer identifies a CXCR4-positive vascular-immune barrier at the T1 stage that excludes T cells ...