Neuropathology-centered approach opens new era for Alzheimer’s disease genetics
A new review argues that shifting Alzheimer's disease genetic research from clinically diagnosed cohorts to neuropathologically confirmed ones is revealing ...
Tag: TDP-43
ALS Protein Clumps Found Far Beyond the Brain Suggest a Whole-Body Disease
A new review finds that the pathological protein TDP-43, the hallmark of ALS, accumulates in muscle, skin, glands and other ...
Glycolytic Enzyme Accelerates ALS by Fueling Inflammatory Neuron Death
New research shows that loss of TDP-43 in ALS drives the glycolytic enzyme ALDOA to trigger inflammatory pyroptotic death of ...
TDP-43 Loss Triggers Broad Polyadenylation Shifts in FTD/ALS
In a groundbreaking study published in Nature Neuroscience, researchers have unveiled that the nuclear depletion of the protein TDP-43 in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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