Tag: Targeting

A comprehensive narrative review indicates that the therapeutic success of post-EVAR type II endoleak embolization depends primarily on vascular anatomy ...

Inhibiting SERPINE1 suppresses cGAS-STING-driven fibroblast senescence and relieves intestinal inflammation in experimental models of Crohn’s disease.

In vitro tests demonstrate that engineered lectin-conjugated liposomes selectively bind high-mannose bladder cancer cells and boost gemcitabine cytotoxicity under simulated ...

Researchers found that naringenin counteracts heat stress-induced downregulation of hepatic OPA1 while reducing biochemical markers of liver injury and oxidative ...

Scientists discover that the mangrove-derived compound dothiortone prevents liver ischemia-reperfusion injury and remote kidney damage by blocking LRG1 and neutrophil ...

Bioinformatics analysis identified AKT1 and NF-κB1 as shared molecular targets linking type 2 diabetes, obesity, and hypertension across four core ...

Engineered exosome-liposome hybrid nanoparticles targeting CSF1R and PD-L1 stimulate macrophage phagocytosis across several brain cancer cell models in vitro, though ...

A new study shows that SRP68 is essential for mouse spermatogenesis, as its loss disrupts ER-mitochondrial contacts and leads to ...

Researchers identified a covalent ethacrynic acid analogue that suppresses lymphoma cell growth and xenografts by disrupting mTOR complexes and inducing ...

Researchers have identified a specific biological mechanism that allows primary effusion lymphoma cells to resist treatment with rapamycin, a common ...