Acute Myeloid Leukemia Reported 32 Months After Icotinib Therapy for EGFR-Mutated Lung Cancer
A case report and literature review describe acute myeloid leukemia developing 32 months into icotinib therapy for EGFR-mutated lung cancer, ...
Tag: Targeted therapy
Combining Liver Artery Therapies With Immunotherapy Shows Survival Gains in Advanced Liver Cancer Review
A meta-analysis of fourteen retrospective cohort studies associates TACE-HAIC combined with targeted therapy and immune checkpoint inhibitors with improved survival ...
Sonrotoclax plus azacitidine induces remission in acute undifferentiated leukemia case
A case report in Annals of Hematology describes a 56-year-old man with newly diagnosed acute undifferentiated leukemia who achieved complete ...
Targeted RAS Drug Shows Survival Benefit Across Advanced Pancreatic Cancer Subgroups
A subgroup analysis of the phase 3 RASolute 302 trial presented at ESMO found the targeted RAS inhibitor daraxonrasib extended ...
Rare NF1-Linked Brain Tumors Show Partial Shrinkage on MEK Blocker Mirdametinib
A retrospective MD Anderson cohort of nine adults with NF1-associated high-grade glioma found partial radiographic responses in two patients treated ...
Editorial: Mechanisms of drug resistance in cancer: overcoming barriers with novel pharmacological strategies
An editorial summarizing eight contributions describes cancer drug resistance as an adaptive process involving genetic, epigenetic, metabolic, signalling and microenvironmental ...
Progress in the Mechanism of Heat Shock Proteins in Gastric Cancer: From Biomarkers to Therapeutic Targets
A narrative review links heat shock proteins to gastric cancer invasiveness, resistance and immune modulation, but finds that most therapeutic ...
Systematic review maps tyrosine kinase inhibitor evidence in canine solid tumours
A systematic review of 200 publications found the clearest clinical evidence for tyrosine kinase inhibitors in canine mast cell tumours, ...
Review maps NSCLC-to-SCLC transformation amid expanding lung cancer treatments
A 2026 literature review synthesizes clinical, diagnostic, molecular and therapeutic evidence on transformation from non–small cell lung cancer to small ...
Review maps mechanisms, diagnosis and treatment of primary cardiac angiosarcoma
A 2026 review summarizes recurrent molecular alterations, immune suppression, multimodal imaging and current treatment strategies for primary cardiac angiosarcoma, a ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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