Epithelial Cells’ Sensitivity to Interferon Gamma May Shape Genital Herpes Outcomes
New research in PLOS Pathogens shows that genital epithelial cells from people with asymptomatic HSV-2 infection respond more strongly to ...
Tag: STAT1
Stem Cell Vesicles Quiet Inflammatory Immune Signals in Osteoarthritis Patients
A new in vitro study reports that mesenchymal stem cell-derived extracellular vesicles reduced Th1 cell frequency, STAT1 expression, and inflammatory ...
Immune Enzyme PTPN2 Emerges as Master Switch in Sepsis Inflammation
McGill University researchers have identified the enzyme PTPN2 as a key regulator of non-canonical inflammasome activation, revealing how it shapes ...
High EBV DNA in Children’s Blood Linked to Immune Imbalance and Secondary Infections
A transcriptomic study of 65 children links high plasma EBV-DNA load to innate immune hyperactivation, impaired adaptive immunity, and a ...
Common Bile Acid Drug Unlocks a Hidden Human Brake on Radiation-Driven Cancer Immunity
Researchers have identified a human-specific FXR-TRIM22-STAT1 checkpoint that suppresses radiation-induced antitumor immunity, and shown that the clinically approved bile acid ...
How Stomach Bacteria Rewire Immune Checkpoints to Fuel Gastric Cancer
A new review explains how Helicobacter pylori virulence factors drive PD-L1 expression in gastric cancer through crosstalk among the NF-κB, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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