Landmark heart atlas reveals two-phase collapse of the failing right ventricle
A multi-platform transcriptomic atlas of the human right ventricle reveals a two-phase progression to failure, with early erosion of protective ...
Tag: Spatial transcriptomics
Machine Learning Pinpoints ANKIB1 as a New Alzheimer’s Biomarker in Brain Insulating Cells
An integrated analysis of single-cell, bulk and spatial transcriptomic data identifies oligodendrocyte palmitoylation as a key dimension of Alzheimer's disease ...
Scientists map the cellular blueprint that sculpts every human face
A new single-cell and spatial atlas of the developing human face identifies 56 cell states, hundreds of spatial patterning genes ...
Macrophage Signal WNT5A Drives Lung Cancer Scarring That Blocks Immunotherapy
A new study reveals how SPP1-positive macrophages secrete WNT5A to activate matrix-remodeling fibroblasts in lung adenocarcinoma, building a stiff tumor ...
New Sequencing Method Captures the Hidden Conversations Between Cells
A new method called CCI-seq captures large-scale cell–cell interaction networks in tissues while preserving full single-cell transcriptomes, revealing interaction-driven gene ...
Hidden Immune Saboteurs: Scientists Map the Cells That Shield Colorectal Tumors
By combining spatial and single-cell transcriptomics, researchers have mapped previously unknown immunosuppressive niches in colorectal cancer, including SPP1-positive macrophage rings ...
First Multiomic Atlas Reveals How the Human Brain’s Protective Layers Build Their Immune Defenses
A paired single-nucleus RNA and chromatin atlas with spatial transcriptomics charts how the human meninges, their blood-brain barrier endothelium, yolk ...
Scientists map the developing human heart cell by cell and reveal how Down syndrome disrupts it
A multimodal atlas of the developing human heart reveals 21 tissue niches, shows fetal pacemaker cells recruiting their own nerve ...
AI Method Reads Tissue Fingerprints to Find Disease Hotspots Earlier
A new deep-learning method called VIMA converts tissue patches into numerical fingerprints and uses rigorous statistics to uncover disease-associated spatial ...
ResolVI cleans up noisy spatial transcriptomics data after segmentation goes wrong
A new probabilistic deep learning model called ResolVI corrects misassigned RNA molecules and batch effects in spatial transcriptomics data, sharpening ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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