Age-Based Genetic Testing Rules May Miss Most Inherited Cancer Risk, Study Finds
A study of nearly 40,000 cancer patients found that age-based germline genetic testing policies would miss about 72 percent of ...
Tag: solid tumors
Four Simple Blood Markers Could Flag Deadly Bacteremia in Cancer Patients Within Hours
Researchers in Seoul have developed a four-variable prediction model combining procalcitonin, pulse rate, neutrophil-to-lymphocyte ratio, and albumin that accurately identifies ...
Hepatitis B exposure declines among cancer patients, yet disparities persist
A fourteen-year Brazilian cohort study of nearly 29,000 cancer patients found hepatitis B virus seroprevalence fell from 16.5 to 9.9 ...
Engineered Macrophages Emerge as a New Frontier in Cell Therapy for Solid Tumors
A new review details how chimeric antigen receptor-engineered macrophages are overcoming the barriers that stalled CAR-T therapy in solid tumors, ...
Viruses That Board CAR Cells: A Modular Push Against Solid Tumors
A new review proposes co-designing oncolytic viruses and CAR-T or CAR-NK cells as a modular, self-amplifying therapeutic system to overcome ...
Two Immune Cell Armies in One Infusion: Combination NK and T Cell Therapy Shows Promise in Hard-to-Treat Tumors
A phase 1 trial found that an autologous combination of natural killer cells and tumor-primed T lymphocytes was safe and ...
Engineered CAR-T Cells That Make Their Own IL-2 Show Stronger Staying Power Against Pancreatic Cancer
A preclinical study shows that CAR-T cells engineered to secrete an Fc-fused IL-2(C125S) variant persist longer, retain mitochondrial fitness, and ...
Engineered T Cells Targeting Hepatitis B Antigen Show Glimmer of Benefit in Advanced Liver Cancer
A case report details how HBsAg-targeted TCR-engineered T cells produced a manageable grade 3 cytokine release syndrome and a transient ...
Rewiring the Engine: How Metabolism Could Unlock CAR-T Cells for Solid Tumors
A new review argues that engineering the metabolism of CAR-T cells, alongside neutralizing the hostile chemistry of tumors, is the ...
CAR-T Cell Therapy Pushes Beyond Blood Cancers Into Solid Tumors and Autoimmune Disease
A sweeping review charts how CAR-T cell therapy has evolved from a blood cancer breakthrough into a versatile platform tackling ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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