Plant-Derived Molecule KGA-1002 Strikes GRP94 to Collapse Liver Cancer’s Protein Folding Machinery
A synthetic guaianolide dimer derived from a plant sesquiterpenoid selectively covalently binds the ER chaperone GRP94 at serine 106, triggering ...
Tag: SKP2
Bortezomib Triggers ROS-Driven Mitochondrial Cell Death and Blocks SKP2 Signaling in Skin T-Cell Lymphoma
New research shows the proteasome inhibitor bortezomib kills cutaneous T-cell lymphoma cells through ROS-dependent mitochondrial apoptosis while suppressing the SKP2-p21/p27 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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