Phosphorylated M18BP1 unlocks human condensin II on DNA
Cryo-electron microscopy and single-molecule experiments show how phosphorylated M18BP1 relieves condensin II autoinhibition, enabling stable DNA binding and compaction in ...
Tag: single-molecule imaging
Hidden Chromatin Domains Emerge When Scientists Watch Single Chromosomes Fold
Single-molecule chromatin tracing in C. elegans embryos has revealed three distinct classes of megabase-scale heterochromatin domains, including condensin-dependent TAD-like structures ...
3D-Nanoprinted Micromirror Brings Gentle Light Sheet Microscopy to Standard Sample Chambers
Researchers at Rice University have developed 3D-nanoprinted reflective micromirror inserts that enable single-objective light sheet microscopy in commercially available sample ...
Chaperone protein guides histone H1 to its nucleosome target, study reveals
Single-molecule experiments show that linker histone H1, essential for compacting and silencing genes, can bind and slide along DNA but ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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