Scientists Catch Muscle Aging in a Dish: A New Lab Model of Skeletal Muscle Senescence
Researchers at the Federal University of Rio de Janeiro have built a primary chick muscle cell culture model in which ...
Tag: SASP
DNA Damage Response Drives PD-L1 Shield That Lets Aging Cells Evade Immune Clearance
A new review proposes that the DNA damage response drives PD-L1 upregulation in senescent cells, enabling immune evasion and creating ...
Sirtuin 1 emerges as the molecular switch linking cellular senescence to heart failure
A new review argues that the longevity enzyme sirtuin 1 sits at the molecular crossroads between cellular senescence and heart ...
The Aging Kidney Gets a Data-Driven Atlas: Machine Learning and Ferroptosis Lead a New Research Era
A sweeping bibliometric analysis of 2,191 papers reveals that kidney aging research has exploded since 2018, with machine learning, ferroptosis, ...
Tiny Cellular Shuttles Drive Aging in Chronic Lung Disease, Review Finds
A new review in the Chinese Medical Journal details how extracellular vesicles spread cellular senescence across chronic lung diseases and ...
Statin-Triggered Liver Aging May Quiet IGF-1 Signals and Shrink Muscle, Study Finds
New research in Cell Death Discovery shows that statins can induce senescence in liver cells, reducing circulating IGF-1 and triggering ...
How Failing Mitochondria Turn Cells Into Engines of Ageing Inflammation
A new GeroScience review details how failing mitochondria act as both initiators and amplifiers of cellular senescence and the chronic ...
Radiation Turns Childhood Brain Tumor Cells Senescent—and Senolytic Drugs Can Kill Them
New research shows that gamma irradiation drives p53 wild-type medulloblastoma cells into a senescent state that senolytic drugs such as ...
Aging Cells Lose Their Recycling Machinery, Letting Senescent Cells Pile Up
New research in Nature Aging shows that the age-related decline of chaperone-mediated autophagy distorts the senescent cell secretome and disables ...
Metabolic Protein ANGPTL8 Found to Accelerate Aging of Blood Stem Cells
New research shows that the metabolic protein ANGPTL8 drives the aging of hematopoietic stem and progenitor cells by binding the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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