Silent Interferon Signals May Flag Ovarian Tumors That Shrug Off Chemotherapy
A cautious reanalysis of single-cell, TCGA, MRI, and cell-line data links muted type-I interferon signaling and altered cell-state programs to ...
Tag: RT-qPCR
Salmonella Response Regulator NarL Found to Control Key DNA Repair Gene
New research shows that the NarL protein binds directly to the promoter of the DNA repair gene ogt in Salmonella ...
Sandwich ELISA Offers Rapid Antigen Test for Feline Coronavirus Detection
Researchers in China have developed a double-antibody sandwich ELISA that detects the feline coronavirus spike protein in faecal samples with ...
Zika Antibody Signals in Pregnant Thai Women Blur the Line Between Zika and Dengue
A prospective cohort study in Thailand found frequent Zika-reactive antibody responses among asymptomatic pregnant women, but negative PCR results and ...
Acrolein-Linked Gene Perturbation Tracks Tumor Immune Heterogeneity in Colorectal Cancer
A toxicogenomic reanalysis links acrolein-responsive gene dysregulation to immune-stromal heterogeneity in colorectal cancer, supported by single-cell localization and RT-qPCR validation ...
AI-Powered Map of Glioblastoma Reveals Tumor Ecosystem States and Immune Programs
A machine-learning-assisted reanalysis of single-cell and bulk transcriptomic data provides a reproducible framework for characterizing glioblastoma ecosystem states while carefully ...
Stable Reference Genes Unlock Reliable Gene Expression Analysis in a Classic Chinese Medicinal Herb
A new BMC Genomics study identifies the first validated stable internal reference genes for accurate RT-qPCR gene expression analysis in ...
Circular RNA Clock Ticks After Death: circRtn4 Emerges as Candidate Marker for Estimating Time of Death
Researchers report that the circular RNA circRtn4 degrades in a predictable, modelable pattern after death in mouse brain tissue, offering ...
One Wet-Lab Measurement May Be Enough to Steer AI-Designed ALS Gene-Silencing Drugs
A biophysics-informed machine learning framework predicts how effectively antisense oligonucleotides knock down ALS-relevant genes using only a single experimental measurement ...
Acne Drug Isotretinoin Calms Inflammation at Gene and Blood Levels, Study Finds
New research shows oral isotretinoin suppresses five key pro-inflammatory cytokines at both gene and protein levels in acne patients, with ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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