Elevated miR-183-5p Impairs Bone-Forming Stem Cells in Scoliosis
A study in BMC Medical Genomics finds that miR-183-5p is upregulated in the serum of adolescent idiopathic scoliosis patients, shows ...
Tag: RT-qPCR
Seven m6A-related genes linked to cuproptosis predict colorectal cancer survival
Researchers built a prognostic model from seven m6A RNA methylation-related genes correlated with cuproptosis genes in colorectal cancer and confirmed ...
Single-Cell Map of Androgen Receptor States in Resistant Prostate Cancer
An exploratory single-cell RNA sequencing study maps androgen receptor-associated cellular states in castration-resistant prostate cancer while explicitly avoiding AR-V7 classification ...
Validated reference genes support RT-qPCR in Cuphea hookeriana
Researchers validated condition-specific reference genes for RT-qPCR normalization in Cuphea hookeriana across four tissues and during exposure to 5 °C.
Lactic Acid Bacteria Reprogram and Displace Mastitis-Associated Staphylococcus aureus Biofilms
An in vitro study shows that three lactic acid bacterial strains from human milk and infant feeding tubes can colonize ...
Hamster blood study reveals hidden flaw in gene expression analysis during infection and vaccination
Researchers identified ppia as the most stable reference gene for RT-qPCR normalization in golden Syrian hamster blood, showing that the ...
Bait-capture sequencing resolves respiratory virus genomes but often misses co-infections
A UKHSA-led evaluation of 61 nasopharyngeal swabs found that bait-enriched whole genome sequencing recovered an average of 85.9 percent of ...
Five-Marker Tissue Model Distinguishes Benign from Malignant Breast Lesions in Internal Validation
A five-marker RNA-based tissue model developed by Chinese researchers distinguished benign from malignant breast lesions with an internal-validation accuracy of ...
Bioinformatics study links two downregulated genes to tendinopathy biomarkers
PTCHD1 and NEURL1 were significantly downregulated in tendinopathy samples, while a gene-based diagnostic model achieved an AUC above 0.7 in ...
Tiny Blood-Based Genetic Clue Could Transform Detection of Childhood Heart Defects
A new study links reduced serum microRNA-122 and the rs9966765 C allele to pediatric congenital heart disease, suggesting a blood-based ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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