LCN2 loss reduces invasion and alters stress pathways in TNBC cells
A CRISPR knockout study in MDA-MB-231 triple-negative breast cancer cells links LCN2 loss to reduced migration, invasion and substrate-dependent adhesion, ...
Tag: RNA sequencing
RNA sequencing maps ToxR-dependent genes in seafood pathogen
RNA sequencing of Vibrio parahaemolyticus at low cell density identified 603 ToxR-dependent genes linking virulence, biofilm development, motility, stress responses ...
Transcriptome SNPs reveal differentiation among 13 conifer provenances
A transcriptome-based analysis of 13 Chamaecyparis hodginsii provenances identified two genetic groups, 10 differentiated genomic regions and preliminary functional candidates ...
Nematode model reveals bacterial shifts in chronic Pseudomonas infection
A C. elegans infection model reproduced part of the transcriptional shift toward chronic Pseudomonas aeruginosa lung infection and identified bacterial ...
Chimeric RNAs produce immune proteins that tune inflammation
A mouse immune-cell study links inflammation-induced chimeric RNA formation to a functional fusion protein that sharpens the trade-off between bacterial ...
Cultivation and gene-expression study links low temperature to Armillaria ostoyae fruiting-body development
An experimental cultivation, transcriptomic, and overexpression study found that low temperature was required for primordium formation in Armillaria ostoyae under ...
Integrative mapping of chloroplast rRNA modifications reveals conserved and lineage-specific features and stepwise modification during plastid ribosome biogenesis
An integrative Arabidopsis study mapped chloroplast rRNA modifications and linked stepwise modification during ribosome biogenesis to rRNA maturation, chloroplast ribosome ...
Genome and expression analysis identifies 215 bZIP genes in LA-Purple sugarcane
A genome and RNA-sequencing study identified 215 bZIP genes in LA-Purple sugarcane and found predicted regulatory features and expression patterns ...
Eight-gene ENE-related RNA signature stratifies metastasis risk and immune features in nasopharyngeal carcinoma
An RNA sequencing study of 159 nasopharyngeal carcinoma patients found that an eight-gene ENE-related signature predicted distant metastasis risk and ...
Metformin Leaves No Robust Gene Signature in Small AMD Trial
A small randomized trial sub-study found no significant individual-gene changes after 18 months of metformin in older adults with age-related ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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