Tag: RNA sequencing

In a mouse model of diet-induced obesity, lipoxin B4 reduced female adipocyte hypertrophy and upregulated ribosomal translation pathways across sexes.

Researchers found that fibroblast activation protein promotes vascular smooth muscle cell migration and neointimal hyperplasia, driving restenosis after surgery for ...

Researchers using nasal epithelium brushing discovered that canine olfactory receptor gene expression varies by more than ten-thousand-fold, with many genes ...

Hemin alleviates lipopolysaccharide-induced acute lung injury in mice by upregulating heme oxygenase-1, which binds to NLRP3 and prevents inflammasome assembly.

An exploratory study shows that IFN-γ–STAT1 signaling is activated in sarcoidosis granulomas and higher pSTAT1 positivity associates with organ-specific disease ...

Silencing STAT1 in human nasopharyngeal carcinoma cells suppressed mesenchymal protein markers and decelerated cellular motility in wound healing assays.

A knock-in mouse study reveals that the cetacean Tbx4-HLEA enhancer delays early embryonic hindlimb bud outgrowth before functional enhancer redundancy ...

Researchers synthesized a mitochondrial fluorescent probe that elevates cellular α-ketoglutarate, downregulates ZNF124, and suppresses colorectal cancer proliferation and metastasis in ...

RNA sequencing of mouse macrophages reveals that distinct Orientia tsutsugamushi strains selectively activate different innate immune signaling pathways and cellular ...

Preclinical experiments demonstrate that OXSR1 deficiency attenuates ischemia-reperfusion-induced acute kidney injury and oxidative stress by inactivating the JAK2/STAT3 pathway.