JuxtaBAM flags mismatched samples in joint multi-omic datasets
JuxtaBAM uses variants discovered within joint epigenomic and transcriptomic datasets to flag possible sample mismatches and duplications without requiring predefined ...
Tag: RNA-seq
CRISPR Editing Route, Not Just Target Genes, Reshapes CHO Cell Lines
A systematic comparison shows that sequential and multiplex CRISPR/Cas9 workflows produce CHO cell lines with the same nine hydrolase knockouts ...
Tiny miR-15a-5p emerges as central switch in ovarian cancer angiogenesis network
An integrated miRNA–mRNA network study in ovarian cancer places miR-15a-5p at the center of an angiogenic module and highlights epithelial ...
Fungi Rewire Their Sugar Metabolism in Surprising Ways to Germinate
A comparative study of five Sordariomycete fungi reveals that spore germination is driven by flexible, redundant mannitol and trehalose networks ...
Airway bacteria share biofilm blueprints but answer stress in their own ways
A comparative RNA sequencing study of eight airway bacteria shows that biofilm formation drives partially conserved functional adaptation, while responses ...
Ancient Secretion System Reveals Its Hidden Arsenal in a Troublesome Lung Pathogen
Researchers have mapped the SigM-controlled regulon in Mycobacterium abscessus, revealing 15 directly induced loci encoding 50 candidate ESX-4 secretion substrates ...
Bacteria Hiding Inside Tumors May Shape Epstein-Barr Virus Activity in Nasopharyngeal Cancer
A paired biopsy study finds that nasopharyngeal carcinoma tissue harbors distinct bacterial communities linked to Epstein-Barr virus activity and immune ...
From Mexico’s First Sequencer to a Global Roadmap: Making Transcriptomics FAIR and Accessible
Two UNAM bioinformaticians distill 17 years of RNA-seq expertise into a strategic roadmap spanning experimental design, de novo assembly, differential ...
A Single Botched Splice May Explain a Deadly Yellow-Leaf Soybean Mutant
Fine mapping of a soybean yellow-leaf lethal mutant has narrowed the cause to a 165-kilobase region on chromosome 10, where ...
Massive Cell-by-Cell Map Reveals the Cerebellum’s Hidden Role in Alzheimer’s Disease
A single-nucleus multiome atlas of over 100,000 brain cells reveals disease-linked regulatory programs and potentially causal genetic variants in the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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