Chemical Tag on RNA Helps Melanoma Dodge Ferroptosis, Study Finds
New research shows that the m6A reader protein YTHDF2 promotes melanoma progression by destabilizing HMOX1 mRNA and shielding tumor cells ...
Tag: RNA methylation
Chemical Tag on mRNA Reveals Hidden Switch That Controls Hair Growth Cycles
A new PLOS Genetics study shows that the RNA modification enzyme METTL1 controls hair follicle cycling by stabilizing HOXC13 messenger ...
Fly Study Reveals How the RNA Modifier Mettl16 Shapes Development and Fertility
New research in fruit flies shows that the RNA methyltransferase Mettl16 is dispensable for survival but essential for fertility, acting ...
Cell cycle clock controls RNA methylation through a hidden ubiquitin code
A new Nature Chemical Biology study reveals that the ubiquitin ligase RLIM tags the m6A writer METTL14 with noncanonical K27-linked ...
RNA Chemical Tag METTL3 Found Essential for Building the Newborn Uterus
A new study shows that the RNA-modifying enzyme METTL3 and its m6A marks are essential for the postnatal specification of ...
Chemical Tags on RNA Hold the Switch That Decides Whether Cells Die of Iron
A comprehensive review maps how m6A RNA methylation regulates ferroptosis across cancer, cardiovascular, neurological and metabolic diseases, revealing new therapeutic ...
An RNA Eraser Gone Rogue: ALKBH5 Emerges as a Molecular Driver of Preeclampsia
New research reveals that the RNA demethylase ALKBH5 drives preeclampsia by erasing m6A marks that stabilize FPR2 messenger RNA, disrupting ...
Chemical Tags on Viral RNA Emerge as a Battleground Between Plants and Pathogens
A new review details how the m6A RNA modification acts as both an antiviral defense and a viral exploitation tool ...
RNA Methylation Enzyme METTL16 Emerges as Guardian of Rod Photoreceptor Survival
New research shows that the RNA methyltransferase METTL16 protects rod photoreceptors by safeguarding splicing fidelity, mRNA stability, and translation, and ...
RNA Tag METTL3 Drives Lung Scarring by Destabilizing a Key Fat-Droplet Protein
New research shows that the RNA methyltransferase METTL3 promotes lipid deposition and pulmonary fibrosis by destabilizing the messenger RNA of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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