Human Argonaute 2 becomes a programmable RNA editing tool
Researchers engineered a programmable RNA base editor called ALTER from human Argonaute 2 fused to APOBEC3A, achieving stronger editing with ...
Tag: RNA editing
Scientists assemble the complete mitochondrial genome of Camellia pitardii
Researchers have assembled the complete 895,290-bp mitochondrial genome of Camellia pitardii, revealing repeat-driven structural plasticity, extensive C-to-U RNA editing and ...
Circular RNA aptamers recruit natural ADAR1 to edit RNA with near-perfect efficiency
A new RNA editing platform called MARRS recruits the cell's own ADAR1 enzyme with engineered circular RNA aptamers, achieving up ...
First Complete Mitochondrial Genome of Chinese Dwarf Cherry Assembled with PacBio HiFi Reads
Using PacBio HiFi long-read sequencing, researchers assembled the first complete circular mitochondrial genome of the Chinese dwarf cherry Prunus humilis, ...
First Mitochondrial Genomes Tie Endangered Hansenia Speciation to Plateau Uplift
The first complete mitochondrial genomes of endangered Hansenia species from the Qinghai-Tibet Plateau reveal varied genome architectures and link the ...
Great Burnet Mitochondrial Genome Assembled to Reveal Rosaceae Evolution
Scientists have assembled the complete mitochondrial genome of Sanguisorba officinalis, a 295,903-base-pair circular molecule whose analysis catalogues 60 genes, 460 ...
RNA editing as an epitranscriptomic immune switch in tumor immunity and cancer immunotherapy
A review in Journal of Translational Medicine describes how dysregulated RNA editing suppresses tumor immune recognition and how programmable RNA ...
RNA Tag m6A Emerges as a Master Switch in Gene Control, Stress and Disease
A review in Nature Reviews Molecular Cell Biology explains how the RNA modification N6-methyladenosine regulates gene expression, enables cellular adaptation, ...
Complete A. venetum mitogenome reveals chloroplast-derived DNA
A complete mitochondrial genome assembly for Apocynum venetum reveals 61 genes, extensive repeats and evidence of intracellular chloroplast-to-mitochondrion gene transfer.
Mitogenome architecture and evolutionary insights in Origanum vulgare: comparative analysis of structural diversity and repeat-mediated recombination
A comparative genomic study assembled and annotated the 497,243-base-pair Origanum vulgare mitogenome, identifying 57 genes, extensive repeat structure and 395 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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