Long Non-Coding RNA MALAT1 Emerges as a Multifaceted Regulator of Bone Remodeling
A new narrative review synthesizes preclinical evidence that the long non-coding RNA MALAT1 influences osteoblast differentiation, osteoclast formation and bone ...
Tag: RNA-binding proteins
Scientists Watch RNA-Binding Proteins Assemble on Nascent Transcripts in Real Time
Fluorescent tagging in living cells reveals the ordered recruitment of RNA-binding proteins to nascent intronless transcripts, including a temporal gap ...
Cutting a Neck Nerve Rewires Gene Networks to Ease Rat Lung Hypertension
In a rat model of pulmonary arterial hypertension, surgically cutting the cervical sympathetic trunk lowered lung pressures and reshaped transcription ...
Hidden RNA Molecule Drives Ovarian Cancer by Stabilizing Two Key Oncoproteins
A long non-coding RNA called RBMS3-AS3 has emerged as a powerful molecular accomplice in ovarian cancer, according to a new ...
Hidden DNA Repeats in the Brain May Shape Splicing and Disease Risk
A large-scale analysis of 336 human prefrontal cortex samples identifies more than 51,000 short tandem repeats linked to alternative splicing ...
RNA-Binding Protein HuR Emerges as a Master Switch in Tau Splicing and Alzheimer’s Genes
A new study identifies the RNA-binding protein HuR as a repressor of tau exon 10 splicing and a regulator of ...
Malaria Parasite RNA Helicase PfDDX1 Emerges as a Regulator of Blood-Stage Development
A new study shows that the conserved DEAD-box RNA helicase PfDDX1 modulates the pace of intraerythrocytic development and gene expression ...
Blocking the Brain’s Cannabis Receptor Repairs Faulty RNA Splicing in Fragile X Mice
A new study in iScience shows that blocking the cannabinoid CB1 receptor with low-dose rimonabant reverses disease-associated alternative splicing defects ...
High Blood Sugar Rewrites Pancreatic Cell Chemistry, Driving Stress Granule Buildup in Diabetes
New research shows that diabetes elevates the histone mark H3K4me1 in pancreatic acinar cells, driving stress granule formation under high ...
TDP-43 Rides Multiple Molecular Motors Along Human Axons, Study Reveals
New research in human neurons shows that the ALS-linked RNA-binding protein TDP-43 is transported along axons by a flexible fleet ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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