Transcriptomic Study Links TAZ to Gut Immune Imbalance in Diabetes
An integrative transcriptomic analysis identifies TAZ as a conserved candidate associated with intestinal Th17/Treg immune imbalance in mouse models of ...
Tag: regulatory T cells
Review Explores Metabolic Reprogramming of Regulatory T Cells in Colorectal Cancer
A review in the Journal of Translational Medicine examines how metabolic reprogramming enables regulatory T cells to drive immunosuppression in ...
Scavenger Receptor and TLR4 Team Up to Drive TGF-β1 and Tregs in Schistosomiasis
SR-A1 cooperates with TLR4 signaling in macrophages to drive TGF-β1 production, inducing regulatory T cells that reduce liver damage during ...
CD276 Blockade Slows Gastric Cancer and Boosts Anti-PD-1 Immunotherapy in Preclinical Study
Blocking the CD276 molecule slowed gastric cancer growth and, combined with anti-PD-1 therapy, produced the strongest tumor suppression and increased ...
Dendritic cells and regulatory T cells reinforce immunosuppression in pancreatic tumors
Single-cell and spatial profiling of pancreatic tumors reveals a reinforcing loop between mature dendritic cells and regulatory T cells, mediated ...
Immune Cells Turned Accomplices: How the Body’s Defenses Help Cancer Spread
A new narrative review in Frontiers in Oncology details how T cells, macrophages, neutrophils, B cells, NK cells, and dendritic ...
NF-κB/Atg5 Axis Linked to Treg Dysfunction in Kidney Antibody-Mediated Rejection
A new study identifies Atg5-dependent Treg regulation as a mechanistic link between Treg dysfunction and macrophage inflammation in kidney antibody-mediated ...
Fibroblasts That Show Tumors’ IDs May Be Shapeshifters, Not Fixed Subtypes
A new perspective argues that antigen-presenting fibroblasts in gastrointestinal tumors are reversible states whose immune role depends on unmeasured co-stimulatory ...
Research report: Baseline immune profiles are associated with positive outcomes in young children with a peanut allergy, enrolled in a randomised clinical trial for oral immunotherapy
A randomised trial in 49 peanut-allergic toddlers found that baseline immune cell profiles and peanut-specific IgE levels were associated with ...
Boosting the Body’s Own Muscle Repair Offers New Hope for Muscular Dystrophy
A new review argues that drugs enhancing the body's own muscle regeneration, exemplified by the approved HDAC inhibitor Givinostat, could ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!