Greatwall Kinase Controls Leukaemia Cell Division Through an Unexpected Non-Canonical Pathway
Researchers discover that Greatwall kinase drives acute myeloid leukaemia cell division independently of the classical ENSA-PP2A pathway.
Tag: Regulates
Study Links DJ-1 Protein to Glioblastoma Growth via UBA52 Signaling Pathway
Researchers found that the protein DJ-1 promotes glioblastoma progression through the UBA52-mediated NF-κB signaling pathway in cell and mouse models.
Retinoic Acid Gradients in Interdigital Tissues Shape Digit Size and Identity
Avian limb studies show interdigital retinoic acid enzyme gradients balance skeletal progenitor proliferation and apoptosis to determine digit size and ...
Cysteine Exposure Produces Divergent Toxin and Macrophage Responses Across C. Difficile Strains
Laboratory tests reveal that twenty millimolar cysteine supplementation triggers diametrically opposite shifts in toxin production and macrophage cytotoxicity between two ...
Polar Front Jet Regulates Moisture Convergence in South China Extreme Rainfall
A study reveals how an extratropical polar front jet and anomalous anticyclones regulated record-breaking extreme rainfall across South China in ...
Circular RNA circBIRC6 Regulates Cisplatin Resistance in Choroidal Melanoma Cells
Researchers have identified that circular RNA circBIRC6 promotes cisplatin resistance in choroidal melanoma cells by sponging miR-503-3p to positively regulate ...
RALY Protein Targets Poly-Uridine Sequences to Control Alternative Splicing
Researchers have identified a specific molecular mechanism by which the protein RALY regulates alternative splicing, a critical process in gene ...
Frontiers retracts bovine embryo mitochondrial biogenesis study
Frontiers in Cell and Developmental Biology retracted a 2025 study on bovine embryo mitochondrial biogenesis due to image integrity concerns.
miR-379-5p Linked to Sepsis Kidney Injury and Survival
A study in BMC Immunology identifies miR-379-5p as a biomarker for sepsis-associated acute kidney injury, linking its low expression to ...
Methionine Restriction Drives Epigenetic Degradation in Aggressive Glioma Brain Tumors
A molecular study reveals that restricting dietary methionine triggers site-specific acetylation and proteasomal degradation of the epigenetic regulator LSD1 in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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