How Lactate Rewrites Cell Fate: The Lactylation–Cell Death Axis That May Define Sepsis
A new review in the Journal of Advanced Research maps how sepsis-driven lactate accumulation chemically rewrites proteins through lactylation, tipping ...
Tag: regulated cell death
How Failing Mitochondria Turn Cells Into Engines of Ageing Inflammation
A new GeroScience review details how failing mitochondria act as both initiators and amplifiers of cellular senescence and the chronic ...
Hydrogel Traps Fleeting Plasma Radicals to Trigger Cancer Cell Death
Researchers have developed a hydrogel that preserves short-lived radicals from cold atmospheric plasma for up to three weeks, triggering disulfidptosis ...
Copper Overload Pushes Cells Toward Death in Wilson Disease
A new review in Cell Death & Discovery links copper overload, mitochondrial failure and regulated cell death pathways including cuproptosis ...
NINJ1: The Membrane-Rupturing Protein That Decides How Cells Die and How Tumors Thrive
A new review in the Journal of Cancer Research and Clinical Oncology examines how the NINJ1 protein executes plasma membrane ...
Scientists Build a Gene-Based Survival Model for Lung Cancer Using a Newly Defined Cell Death Pathway
Researchers constructed a fourteen-gene triaptosis-related prognostic model for lung adenocarcinoma using transcriptomic analysis, machine learning, single-cell sequencing, and experimental validation.
New necroferrins strategy simultaneously targets necroptosis and ferroptosis
A new review in Ferroptosis and Oxidative Stress examines whether one class of compounds could suppress two interconnected forms of ...
Glycerophospholipids’ Redox Role in Ferroptosis Therapy
Iron, a pivotal biometal, commands a unique position at the crossroads of life and cell death, wielding profound influence over ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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