RNA-Binding Protein Switch Could Sensitize Deadly Pancreatic Cancer to Radiation
Researchers in Beijing have identified a PUM2-PAFAH1B1 regulatory axis that triggers ferroptosis and overcomes radioresistance to iodine-125 seed therapy in ...
Tag: radioresistance
Radiotherapy Backfires: PD-1-Positive Monocytes Emerge as Hidden Drivers of Treatment Resistance
New research reveals that radiotherapy induces PD-1 expression on tumor-associated monocytes through an adenosine-driven signaling pathway, creating an immunosuppressive cell ...
Viral Saboteur Unmasked: How EBV Silences a Key Immune Molecule to Drive Nasopharyngeal Cancer
A new review in Cancer Immunology, Immunotherapy details how EBV-encoded miR-BART4 suppresses the innate immune molecule BPIFB1/LPLUNC1, whose loss promotes ...
Hidden Protein Trio Helps Cancer Cells Survive Radiation, Study Finds
A newly identified TIMELESS-SIRT1-Ku70 complex promotes assembly of the Ku DNA repair heterodimer, giving cancer cells resistance to radiation and ...
Scientists Reverse Radiotherapy Resistance in Lung Cancer by Rewiring the Immune Microenvironment
New research shows that lung tumors become radioresistant through ATR signaling activation and immune suppression, but innate immune agonists and ...
Motor Protein KIFC1 Fuels Cervical Cancer Radioresistance Through a Splicing-Driven Glycolytic Switch
New research reveals that the motor protein KIFC1 drives cervical cancer radioresistance by shuttling the splicing factor SRSF3 into the ...
RNA Acetylation Enzyme NAT10 Helps Glioblastoma Resist Radiotherapy
Researchers found that the RNA acetyltransferase NAT10 helps glioblastoma resist radiotherapy by stabilizing SLC7A11 mRNA and blocking immunogenic ferroptosis, and ...
How a Single Chemokine Can Sabotage Radiotherapy and Shape the Immune Battlefield
A new review explains how radiation-induced CCL2/CCR2 signaling recruits immunosuppressive myeloid cells and remodels the tumor microenvironment, and why combining ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!