Cell Death Protein GSDME Emerges as Ominous Sign for Gastric Cancer Patients
New research shows that the pyroptosis executor GSDME is upregulated in gastric cancer, where it correlates with advanced stage, immunosuppressive ...
Tag: pyroptosis
Hidden Brain Protein Reveals New Cell Death Pathway After Concussion
Researchers report that the trafficking protein Snapin drives neuronal PANoptosis after mild traumatic brain injury by disrupting hydrogen sulfide signaling ...
Bioprinted Coronary Artery Model Recreates Kawasaki Disease in the Lab
A 3D bioprinted human coronary artery equivalent reproduces Kawasaki disease vasculitis using patient serum and enables rapid drug screening.
CASP9 Emerges as a Double-Edged Gene in Kidney Cancer, Study Finds
A multi-omics study identifies CASP9 as a genetically protective but stage-dependent prognostic factor in clear cell renal cell carcinoma, linking ...
Hidden Protein From Circular RNA Shields Colon Cancer Cells From Fiery Death
A circular RNA derived from the PIAS1 gene encodes a previously unknown 108-amino-acid protein that colon cancer cells use to ...
Inflammatory Cell Death Emerges as a Driver of Ovarian Dysfunction and Infertility
A new review in Reproductive Sciences details how the inflammatory cell death pathway pyroptosis drives ovarian dysfunction and infertility, and ...
Plant Compound Monotropein Shows Promise Against Stroke Damage by Taming a Key Inflammasome
A new rat study finds that monotropein, a compound from the medicinal plant Morinda officinalis, protects the brain from ischemia/reperfusion ...
Sono-Activated Platinum-Manganese Nanodendrites Trigger Ferroptosis and PANoptosis to Defeat Drug-Resistant Breast Cancer
Engineered platinum-manganese nanodendrites activated by ultrasound concurrently trigger ferroptosis and PANoptosis, overcoming cisplatin resistance in breast cancer models.
Three Ways to Die: How Ferroptosis, Cuproptosis and Pyroptosis Shape Cancer
A new Molecular Cancer review proposes an "interconnected death" framework showing how ferroptosis, cuproptosis, and pyroptosis interact through shared metabolic ...
Tiny RNA Molecule Triggers Explosive Cell Death in Aggressive Breast Cancer
Researchers have discovered that the microRNA miR-205-3p triggers inflammatory pyroptotic cell death in triple-negative breast cancer by repressing HSP90AB1, while ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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