Reduced fruquintinib dose showed no significant survival association in colorectal cancer cohort
In a multicenter retrospective cohort of 69 patients with refractory metastatic colorectal cancer, an initial fruquintinib dose below 5 mg ...
Tag: proteinuria
How Infection Signals Push Kidney Filter Cells Into Leaks, Damage, and Cell Death
New research shows that sustained activation of the innate immune receptor TLR4 in podocytes triggers a reversible leak in the ...
Finerenone Slows Kidney Decline in Non-Diabetic CKD, Real-World Study Finds
A 24-month real-world cohort study of 121 patients with non-diabetic chronic kidney disease found that finerenone initiation was associated with ...
Kidney Damage Emerges as Hidden Complication in Beta-Thalassemia Survivors
A clinical study finds that albuminuria and proteinuria are common in beta-thalassemia major patients and vary with age and iron ...
Inflammatory Fatty Acid Drains Kidney Cells’ Energy Supply, Worsening Podocyte Damage
New research shows that arachidonic acid released during infection worsens podocyte kidney injury by disrupting PKM2-linked glycolytic metabolism and mitochondrial ...
Complement biomarkers emerge as key guides in the new era of IgA nephropathy therapy
A new review maps how complement-related biomarkers in blood, urine and kidney tissue could guide diagnosis, prognosis and targeted therapy ...
Lupus nephritis study finds proteinuria drop at 12 months best predicts survival
For patients whose immune systems turn against their own kidneys, the single most important question is deceptively simple: how will ...
When Lymphoma Masquerades as Kidney Disease: A Rare Case of Light Chain Amyloidosis
A rare case report describes severe renal light chain amyloidosis arising from low-grade B-cell non-Hodgkin lymphoma, diagnosed through renal biopsy ...
Kidney Cells Switch On a Cholesterol Program When Flooded by Protein, Study Finds
A donor-aware single-cell analysis links membranous nephropathy to an LXR-linked cholesterol-handling state in kidney tubule cells and reveals a matching ...
RNA Chemical Tag Emerges as Hidden Driver of Kidney Damage in Diabetes
A new study shows that the RNA demethylase FTO stabilizes EGR1 mRNA through m6A modification, activating a STING1-driven inflammatory cascade ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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