Redundant protein experiments fused into a ranking model for variant effects
Overlapping deep mutational scanning experiments were fused into a consensus variant soundness score that trained ESMRank, a sequence-based learning-to-rank model ...
Tag: protein language model
Yak collagen peptides inhibit MMP-1 and extend worm lifespan
A computational and experimental study identified three yak bone collagen peptides that inhibited MMP-1 and extended the lifespan of Caenorhabditis ...
AI Language Model Redesigns Hemoglobin for Stronger Oxygen Binding
Using the ESM3 protein language model, researchers engineered a hemoglobin variant with enhanced stability, heme binding, and oxygen affinity, validated ...
Lightweight AI Tool Outsmarts Deep Learning at Spotting Disordered Proteins
A researcher at IIIT Allahabad has developed IDP-T5CKNN, a lightweight protein language model method that outperforms more than 20 existing ...
New AI Model Rewires Molecular Graphs to Predict How Tightly Drugs Bind Their Targets
A new dual-graph deep learning framework called CGA-DTA conditions molecular graph topology on the binding partner and applies cross-graph attention ...
New AI model maps the entire protein universe in a single view
An international research team has developed CLSS, a protein language model that unites amino acid sequence and structural information into ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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