Plants’ Double-Headed Defenders: How Multifunctional Enzyme Inhibitors Could Reshape Crop Protection
A new review in Plant Molecular Biology defines plant multifunctional inhibitors as a distinct class of double-headed defense proteins and ...
Tag: Protein Engineering
Tiny Photoswitchable Protein Opens a New Window on Deep-Tissue Molecular Imaging
Researchers engineered an 18.8-kilodalton photoswitchable near-infrared protein, rsmiRFPnano, that enables background-free photoacoustic imaging of inflammation signaling and intracellular antigens deep ...
Hepatitis C Vaccine Design Gains Ground as Structures Reveal How Naive Antibodies See Viral Envelope
New structural and biochemical analyses of the hepatitis C virus E2 glycoprotein show that germline-reverted broadly neutralizing antibodies recognize the ...
Four Proteins, One Machine: Scientists Decode How Bacterial R-Bodies Assemble and Snap Open
Researchers at Institute of Science Tokyo have revealed how four proteins cooperate through a regulated assembly pathway to build pH-responsive, ...
Protein Therapy Aims to Restore Brain Function in Fragile X Syndrome
A UC Riverside team funded by FRAXA will test engineered proteins designed to cross the blood-brain barrier and normalize brain ...
Deep Learning Reads Molecular Dynamics to Decode Protein Allostery
A new graph neural network framework called AlloPool distills molecular dynamics simulations into minimal, time-resolved interaction networks that reveal how ...
DyME: A New Engine Automates Thousands of Protein Simulations for Molecular Design
Researchers have developed DyME, an open-source platform that automates high-throughput mutagenesis, molecular dynamics simulation, and comparative analysis of thousands of ...
Global AI protein design contest puts 12,000 computer-made cancer binders to the test in living T cells
A global competition benchmarked 12,000 AI-designed CD20 binders in primary human CAR-T cells, revealing common design failure modes and simple ...
AI-Designed Protein Binders Face Real-World Test in Landmark CAR T Cell Competition
A crowdsourced competition called Bits to Binders tested 12,000 AI-designed minibinders as CAR T cell recognition domains, revealing both the ...
AI Meets Catalysis: A New Scientific Paradigm Is Emerging
A new bibliometric review reveals that artificial intelligence and catalysis, despite explosive individual growth, intersect in only 0.02 percent of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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