Hidden Androgen Receptor Isoform Shows Promise Against Kennedy’s Disease
A naturally occurring short isoform of the androgen receptor, AR-A, dramatically reduces aggregation and toxicity of the mutant protein causing ...
Tag: Protein aggregation
Human ALS Seeds Transmit Two Distinct SOD1 Aggregation Strains in Mice
Seeds prepared from the spinal cords of ALS patients homozygous for the SOD1 D90A mutation transmitted two distinct strains of ...
Polyubiquitin Repositioning Reshapes Pathological Tau Fibril Structures in Dementia
Cryo-electron microscopy reveals that repositioned polyubiquitin chains outside the ordered core can remodel tau fibril ultrastructure and shift the protofilament ...
Unique amyloid-β filament structure found in APP Flemish mutation carriers
Cryo-electron microscopy has revealed an entirely new amyloid-β filament fold in the brains of individuals carrying one of the rarest ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!