Starvation enzyme SIRT2 strips a mitochondrial gatekeeper to trigger cell death
Researchers at Army Medical University show that during prolonged starvation the deacetylase SIRT2 moves into mitochondria, removes an acetyl group ...
Tag: programmed cell death
How a Rare Medicinal Plant Builds Its Silkworm-Like Rings: Multi-Omics Study Reveals the Mechanism
A multi-omics study reveals that the prized silkworm-like rings of the medicinal plant Notopterygium incisum form through uneven secondary growth, ...
Scientists Uncover the Secret Weapon a Watermelon-Killing Fungus Uses to Blind Plant Defenses
Researchers have shown that the secreted protein FonCHRD is essential for growth, spore formation, and virulence in the fungus that ...
The Don’t Eat Me Signal: How CD47 Shapes Cell Clearance in Cancer, Heart Disease and the Brain
A new review details how the CD47 don't eat me signal regulates efferocytosis and shapes disease outcomes in cancer, atherosclerosis ...
Hidden Brain Protein Reveals New Cell Death Pathway After Concussion
Researchers report that the trafficking protein Snapin drives neuronal PANoptosis after mild traumatic brain injury by disrupting hydrogen sulfide signaling ...
Chemical Tags on RNA Hold the Switch That Decides Whether Cells Die of Iron
A comprehensive review maps how m6A RNA methylation regulates ferroptosis across cancer, cardiovascular, neurological and metabolic diseases, revealing new therapeutic ...
RNA Modification and Cell Death Genes Point to New Prognostic Tool for Ovarian Cancer
Researchers built a machine learning gene signature combining RNA modification and programmed cell death biology that predicts survival and immunotherapy ...
Wheat’s LIFEGUARD Gene TaLFG32 Emerges as a Hidden Ally of Stripe Rust
Researchers in China have identified 32 wheat LIFEGUARD genes and shown that the membrane protein TaLFG32 suppresses reactive oxygen species ...
Cell Death Regulator BI-1 Emerges as Key Switch in Plant Immunity Against Oomycete Pathogens
New research identifies the ER-localized cell death regulator BI-1 as a key executor of Arabidopsis resistance to Phytophthora parasitica, controlled ...
Three Ways to Die: How Ferroptosis, Cuproptosis and Pyroptosis Shape Cancer
A new Molecular Cancer review proposes an "interconnected death" framework showing how ferroptosis, cuproptosis, and pyroptosis interact through shared metabolic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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