Nanoparticles may carry CRISPR gene editing into infant neuroblastoma
Infant neuroblastoma is one of the most clinically paradoxical cancers in medicine. Diagnosed during the first year of life, it ...
Tag: prime editing
PrimeStack: New Gene-Stacking Tool Writes Large DNA Cargos Into Rice Genomes at Precise Sites
Scientists have developed PrimeStack, a break-free genome-editing platform that combines prime editing with the Bxb1 integrase to insert large multigene ...
Scientists Engineer Supercharged Herbicide-Resistant Crops by Editing Protein and Promoter Together
Researchers have combined structure-guided protein design with cis-regulatory enhancer insertion to create rice and wheat plants that tolerate herbicide doses ...
Cellular family trees: scientists map how one cell builds an entire mouse
Two independent HHMI teams have used DNA recording technologies to reconstruct the most complete cellular family trees ever made for ...
CRISPR Multiplex Editing Emerges as a Master Key for Stress-Resilient Crops
A new review in Plant Cell Reports charts how CRISPR multiplex genome editing has become the definitive tool for mapping ...
CRISPR Multiplex Gene Editing Rewrites the Rules of Crop Breeding
A new review details how CRISPR-based multiplex genome editing is enabling breeders to stack disease resistance, yield and quality traits ...
CRISPR’s Journey From Molecular Scissors to Precision Genome Editors
A new review traces how CRISPR genome editing has evolved from blunt molecular scissors into increasingly precise therapeutic tools for ...
Prime Assembly Enables Targeted Genomic Integration and Large-Scale DNA Rearrangements
A new prime editing-based strategy called prime assembly enables precise integration of large DNA fragments and programmable genomic rearrangements without ...
DNA-Binding Protein Fusions Supercharge PAM-Flexible, High-Precision Base Editing
Researchers have fused HMGN1 and VP64 to a PAM-flexible, truncated-CDA1 base editor, boosting precision and efficiency for editing nearly any ...
Prime Editing Gets a Size Upgrade: Researchers Insert Large DNA Fragments with Precision
Researchers report a prime-editing strategy that integrates large DNA fragments into precise genomic sites through donor-directed annealing without double-strand breaks.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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