Chemical Tags on Blood Proteins Reveal a New Window Into Alzheimer’s Disease
Researchers at the University of Tokyo have produced the first map of lysine acetylation marks across plasma proteins in Alzheimer's ...
Tag: post-translational modification
Inside the cilium: how dynein motors are tuned by a web of regulatory signals
A new review in Cellular and Molecular Life Sciences details how dynein motor proteins in the ciliary axoneme are regulated ...
Rotten-Egg Gas Arms Wheat Against Rust by Switching On Cellular Recycling
New research shows that hydrogen sulfide enhances wheat resistance to stripe rust by persulfidating the autophagy protein TaATG6c, thereby activating ...
Hydrogen Sulfide’s Hidden Hand: How a Tiny Gas Molecule Rewires Plant Proteins
A new review in Plant Cell Reports establishes protein persulfidation, a hydrogen sulfide-driven modification of cysteine residues, as a central ...
Lactate Tags a Tumor Suppressor and Fuels Liver Cancer Growth
Researchers report that lactate-driven lactylation of the tumor suppressor OVOL2 at lysine 3, catalyzed by KAT8, weakens its nuclear function ...
Molecular Off Switch: Enzyme That Strips SUMO Tags Decides When Arabidopsis Seeds Wake Up
A new study shows that the SUMO protease ASP1 removes regulatory tags from the chromatin protein AL6, promoting its degradation ...
Viral tug-of-war: palmitoylation switch governs geminivirus infection in plants
A new study shows that reversible S-palmitoylation of the geminiviral C4 protein, controlled by the opposing host enzymes NbPAT4 and ...
AI Framework Reads the Literature to Map Protein Modifications It Was Never Trained On
Researchers have developed GenPTM, a text-mining framework that extracts protein post-translational modification information from scientific abstracts and generalizes to modification ...
Tiny Worms Forge Fake Plant Hormones to Hijack Crop Roots
A new review reveals how sedentary plant-parasitic nematodes forge peptide hormones that mimic the plant's own signals, hijacking receptor pathways ...
Epigenetic Enzyme Keeps Spinal Disc Cells Metabolically Balanced, Study Finds
New research shows that the epigenetic enzyme HDAC1 preserves metabolic balance in nucleus pulposus cells through post-translational modification interactions with ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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