Estimating metabolic pathway overlap in precision oncology: integrating pharmacogenetics and polypharmacy
Only a small fraction of the drugs recommended for gastrointestinal cancers are directly steered by known pharmacogenetic variants, yet the ...
Tag: phenoconversion
Subtle cognitive deficits emerge before ALS symptoms appear, study finds
A longitudinal study of people carrying ALS genetic variants found mild cognitive impairment, mainly affecting language and executive functioning, in ...
Large Language Models Could Help Detect Pharmacogenomic Phenoconversion
A 2026 perspective proposes that large language models could integrate genetic and clinical records to identify possible pharmacogenomic phenoconversion, while ...
Hidden Drug Metabolism Shifts May Drive Rural Pain Care Inequities in Older Adults
Researchers propose that unrecognized drug-drug-gene interactions known as phenoconversion contribute to pain treatment failures and harm in rural older adults, ...
Blood Test Combo Flags Who Will Develop Parkinson’s Disease Years Early
A new PPMI analysis shows that combining a blood-based microRNA-7-5p measurement with the alpha-synuclein seed amplification assay can identify prodromal ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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