Histone readers MLLT1 and MLLT3 concentrate AID to confer locus specificity
New research in Nature shows that the histone readers MLLT1 and MLLT3 license the antibody-mutating enzyme AID at specific genomic ...
Tag: phase separation
Splicing factor SRSF1 tunes nucleolar cap pH to rescue ribosome factories after stress
A new Nature Chemical Biology study shows that the splicing factor SRSF1 is recruited to dark nucleolar caps under stress, ...
Liquid Droplets Inside Cancer Cells Explain Why a Leukemia Drug Works So Slowly
A new Cell Research study shows that BCR-ABL1 forms liquid-like phase-separated condensates inside leukemic cells that physically slow tyrosine kinase ...
Cohesin Builds Molecular Fences That Keep Active Genome Domains From Mixing
New research shows that the cohesin complex acts as a molecular barrier in living human cells, preventing condensed euchromatic domains ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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