Subtle Shape Shifts, Not Misfolding: How FUS Mutations Drive ALS
A computational study shows that ALS-linked FUS mutations cause disease through subtle, site-specific changes in protein flexibility and molecular recognition ...
Tag: phase separation
Physicists Map the Invisible Forces That Fold the Human Genome Inside the Nucleus
A new opinion article explains how phase separation, loop extrusion, and nuclear membrane adsorption together shape the 3D folding of ...
How Molecular Flux and Rigid β Motifs Drive Fibril Growth at Condensate Interfaces
New simulations reveal that rigid β-prone motifs and the rate of molecular delivery jointly determine whether aging condensate interfaces spread ...
Cytomegalovirus Hijacks Host Chromatin Remodeler MORC2 to Fuel Viral Genome Repair
A new PLOS Pathogens study shows that human cytomegalovirus induces and recruits the host chromatin remodeler MORC2 to viral replication ...
Plants Build Their Own Sunscreen From Protein Condensates Under Intense Light
A Nature Plants highlight describes how singlet oxygen triggers MBS1 protein condensates that shield chloroplasts from excess light, and how ...
Mutations Give RNA Droplets Their Own Genes, Vacuoles and Movement
Researchers have shown that RNA droplets trap their own DNA templates, and that even low rates of mutation produce stable ...
Heat Stress Drives a Fertility Protein Into Worm Germ Cell Granules, Revealing a New Stress Response
New research in C. elegans shows that the conserved stress granule protein GTBP-1 reorganizes into P-body-associated granules during heat stress ...
Dunes Follow a Hidden Physics: Young Coastal Dune Landscapes Self-Organize Like Phase-Separating Fluids
New research shows that young coastal dune landscapes self-organize through phase-separation physics, revealing local tipping points beyond which damage to ...
Spray-Coated Self-Stratifying Fibers Supercharge Triboelectric Nanogenerators
South Korean researchers have developed a one-step spray-coating method that self-assembles stratified PDMS/P(VDF-TrFE) fibrous composites for high-performance, durable triboelectric nanogenerators ...
Molecular Chaperones Keep ALS Protein Droplets From Hardening Into Disease
A new review in BMC Medicine argues that ALS arises when the cellular systems that keep reversible protein condensates from ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!