Enzyme Replacement Therapy Proves Safe and Stable in Chinese Patients with Fabry Disease
A 52-week phase 3 trial across six Chinese centers found agalsidase alfa was generally well tolerated, kept kidney and cardiac ...
Tag: phase 3 trial
Once-Daily Tapinarof Cream Shows Strong 60-Week Results in Young Children With Eczema
A 60-week phase 3 trial found that once-daily tapinarof cream 0.5% significantly outperformed vehicle and maintained efficacy and safety in ...
Immunotherapy Boost for Bile Duct Cancer Survival Holds Firm After Three Years
Three-year follow-up of the phase 3 KEYNOTE-966 trial confirms that adding pembrolizumab to gemcitabine and cisplatin chemotherapy maintains a durable ...
Radioactive Tiles Implanted During Surgery Halve Recurrence Risk in Brain Metastases Trial
A Phase 3 trial found that cesium-131 collagen tiles implanted during brain metastasis surgery reduced one-year recurrence to 1.3 percent ...
Statistical Rework Reveals Even Larger Survival Gain for Kidney Cancer Drug Combination
A two-stage estimation analysis of the CheckMate 9ER trial shows that removing the influence of subsequent therapy substantially enlarges the ...
Oral Giredestrant Combination Nearly Doubles Survival Without Progression in Metastatic Breast Cancer
The phase 3 evERA study found that an all-oral combination of the next-generation estrogen receptor degrader giredestrant and everolimus significantly ...
Five-Year Trial Shows Interferon Outperforms Hydroxyurea Molecularly in Myeloproliferative Neoplasms
The Danish DALIAH phase 3 trial found that low-dose pegylated interferon achieved superior long-term molecular responses to hydroxyurea in myeloproliferative ...
Antibody-Drug Combination Falls Short in First-Line PD-L1-High Metastatic Lung Cancer Trial
The Phase 3 EVOKE-03/KEYNOTE-D46 trial found that sacituzumab govitecan plus pembrolizumab did not significantly improve progression-free or overall survival compared ...
Six Months of Chemotherapy Before Surgery Matches Four-Month Course in Pancreatic Cancer
The PACT-21/CASSANDRA phase 3 trial found that six months of preoperative chemotherapy produced event-free survival comparable to a four-month preoperative ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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