Intranasal creatine prodrug shows early brain activity in phase 1 trial
A phase 1 trial found that intranasal creatine prodrug CBT101 was tolerated and produced exploratory EEG changes consistent with central ...
Tag: Phase 1 trial
First DS1025 dose administered in international Phase 1 solid-tumor trial
Kansai Medical University Hospital gave the first worldwide dose of investigational CD25-directed antibody drug conjugate DS1025 in a global Phase ...
Needle-Free Blood Draw Device Keeps IV Lines Open Through Intensive Pharmacokinetic Studies
A pilot study shows a needle-free blood collection device can sustain nine venous samples per visit through a single IV ...
Longer Gap Between Doses Boosts Durability of Self-Amplifying mRNA H5N1 Flu Vaccine in Phase 1 Trial
A Phase 1 trial found that an eight-week dosing interval produced stronger and longer-lasting antibody responses against H5N1 influenza than ...
Experimental Whole-Virus Flu Vaccine Shows Safety and Broad Immune Signals in First Human Trial
A phase 1 trial found that the BPL-1357 whole-virus inactivated influenza vaccine was well tolerated and induced broad antibody responses ...
ATR Inhibitor Ceralasertib Paired With Olaparib Shows Promise in BRCA-Mutant Breast Cancer
A Phase 1 trial found that combining the ATR inhibitor ceralasertib with the PARP inhibitor olaparib was generally well tolerated ...
Two Immune Cell Armies in One Infusion: Combination NK and T Cell Therapy Shows Promise in Hard-to-Treat Tumors
A phase 1 trial found that an autologous combination of natural killer cells and tumor-primed T lymphocytes was safe and ...
Glutamine Joins Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Cancer Trial
The phase 1 GlutaPanc trial shows that l-glutamine can be safely combined with first-line gemcitabine and nab-paclitaxel in advanced pancreatic ...
Antibody-Drug Conjugate Hits Recommended Phase 3 Dose in EGFR-Mutated Lung Cancer
An investigational EGFR x HER3 antibody-drug conjugate showed promising efficacy and a manageable safety profile in previously treated EGFR-mutated lung ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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