Single-Dose Oral NEPA Shows Promise Against Chemotherapy Nausea in Children
A phase 2 dose-finding trial found that a single oral dose of the netupitant-palonosetron combination NEPA effectively prevented chemotherapy-induced nausea ...
Tag: Pharmacokinetics
Herbal Remedies Quietly Reshape Blood Thinner Levels in Healthy Volunteers
A clinical trial finds that the traditional Korean formulations Bojungikgitang and Cheongsanggyeontongtang substantially raise or lower edoxaban exposure in healthy ...
Generic Diabetes Drug Teneligliptin Proves Bioequivalent in Chinese Volunteers
A randomized crossover trial in 52 healthy Chinese adults found that a generic teneligliptin hydrobromide tablet met all regulatory bioequivalence ...
Melatonin’s Many Promises Face a Pharmacokinetic Reality Check
A new review argues that melatonin's non-sleep therapeutic claims must be re-evaluated through measured drug exposure, since oral bioavailability is ...
Drug Interactions and Side Effects Shape Safe Prescribing of Lung Cancer Pills
A comprehensive review maps how food, acid-reducing drugs and liver enzymes alter the exposure of thirty lung cancer targeted therapies, ...
Subcutaneous Tarlatamab Shows Safety and Early Activity in Small Cell Lung Cancer
A phase 1b study presented at the IASLC 2026 World Conference on Lung Cancer found that subcutaneous tarlatamab was well ...
New Study Tracks How Bilirubin Moves Through Preterm Infant Bodies
A 2026 Journal of Perinatology study examines how bilirubin production, distribution, and clearance differ in preterm infants, informing safer jaundice ...
Black Pepper Compound Piperine Emerges as Powerful Potential Parkinson’s Drug in Landmark Study
A new computational study shows that piperine, the pungent alkaloid of black pepper, binds the Parkinson's-related MAO-B enzyme more strongly ...
Conducting Polymer Coating Turns Ordinary Electrode Into Ultra-Sensitive Detector of Bladder Drug
Researchers in India have developed a polyaniline-coated glassy carbon electrode that detects the overactive bladder drug oxybutynin hydrochloride down to ...
Body Composition May Predict Chemotherapy Toxicity in Early-Stage Breast Cancer
A new review finds that muscle mass, fat distribution, and sarcopenic obesity strongly influence chemotherapy toxicity in early-stage breast cancer, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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