Nationwide Study Identifies Inappropriate Medications at Polypharmacy Initiation in France
A nationwide descriptive cross-sectional study of 693,309 adults aged 45 years and older initiating polypharmacy in France has revealed that ...
Tag: pharmacoepidemiology
Simulation Study Reveals Bias in Self-Controlled Drug Safety Designs
A simulation study finds that exposure time trends significantly bias estimates in self-controlled drug safety designs, with case-crossover showing the ...
Colchicine fails to cut cardiovascular risk in Chinese adults starting urate-lowering therapy
A large Beijing claims cohort found no link between colchicine use and cardiovascular disease risk in adults without prior heart ...
Long-Term NSAID Use Linked to Higher Risk of Knee Replacement Surgery
A large nested case-control study found that patients using non-steroidal anti-inflammatory drugs for knee osteoarthritis for more than five years ...
SGLT2 Inhibitors Outperform DPP-4 Inhibitors in Safety for Super-Elderly Diabetic Patients
A large propensity score-matched study reveals that super-elderly diabetes patients initiating SGLT2 inhibitors experienced significantly fewer falls, fractures, and kidney ...
Multidisciplinary Support Linked to Lower Antibiotic Prescriptions in French Nursing Homes
An observational study of 655 nursing homes in France found that multidisciplinary antibiotic team support was associated with lower antibiotic ...
Japan’s EHR Databases Face Standardization Hurdles for Regulatory Use
A review of eight Japanese EHR databases highlights their broad data coverage but identifies critical gaps in standardization and patient ...
Breast Cancer Survivors Use More Chronic Disease Medications, Nationwide Study Finds
A nationwide Norwegian cohort study found that female breast cancer survivors use medications for chronic conditions, especially anxiety and steroid-responsive ...
Early Adherence to Menopausal Hormone Therapy Linked to Lower Frailty Risk
A nationwide Korean target trial emulation study found that early adherence to menopausal hormone therapy was associated with a lower ...
Antipsychotic Prescriptions Drop in Pregnancy, Surge After Birth in Japanese Claims Study
A large Japanese claims database study found antipsychotic prescriptions declined during pregnancy and rebounded after delivery, with schizophrenia diagnoses showing ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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